Kelly Bales: search on Z-Library

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1

Passive immunotherapy targeting amyloid-β reduces cerebral amyloid angiopathy and improves vascular reactivity

Bales, Kelly R., O’Neill, Sharon M., Pozdnyakov, Nikolay, Pan, Feng, Caouette, David, Pi, YeQing, Wood, Kathleen M., Volfson, Dmitri, Cirrito, John R., Han, Byung-Hee, Johnson, Andrew W., Zipfel, Greg

Journal:

Year:

2015

Language:

english

File:

PDF, 1.22 MB

english, 2015

2

Translocator protein in late stage Alzheimer’s disease and Dementia with Lewy bodies brains

Xu, Jinbin, Sun, Jianjun, Perrin, Richard J., Mach, Robert H., Bales, Kelly R., Morris, John C., Benzinger, Tammie L. S., Holtzman, David M.

Journal:

Annals of Clinical and Translational Neurology

Year:

2019

Language:

english

File:

PDF, 2.01 MB

english, 2019

3

Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo

John R. Cirrito, Kelvin A. Yamada, Mary Beth Finn, Robert S. Sloviter, Kelly R. Bales, Patrick C. May, Darryle D. Schoepp, Steven M. Paul, Steven Mennerick, David M. Holtzman

Journal:

Year:

2005

Language:

english

File:

PDF, 347 KB

english, 2005

4

ApoE and Clusterin Cooperatively Suppress Aβ Levels and Deposition: Evidence that ApoE Regulates Extracellular Aβ Metabolism In Vivo

Ronald B DeMattos, John R Cirrito, Maia Parsadanian, Patrick C May, Mark A O'Dell, Jennie W Taylor, Judith A.K Harmony, Bruce J Aronow, Kelly R Bales, Steven M Paul, David M Holtzman

Journal:

Year:

2004

Language:

english

File:

PDF, 304 KB

english, 2004

5

P-glycoprotein deficiency at the blood-brain barrier increases amyloid- $\beta$ deposition in an Alzheimer disease mouse model

Cirrito, John R, Deane, Rashid, Fagan, Anne M, Spinner, Michael L, Parsadanian, Maia, Finn, Mary Beth, Jiang, Hong, Prior, Julie L, Sagare, Abhay, Bales, Kelly R, Paul, Steven M, Zlokovic, Berislav V,

Year:

2005

Language:

english

File:

PDF, 663 KB

english, 2005

6

Immunotherapy for Alzheimer's disease: will vaccination work?

Jean-Cosme Dodart, Kelly R. Bales, Steven M. Paul

Journal:

Trends in Molecular Medicine

Year:

2003

Language:

english

File:

PDF, 128 KB

english, 2003

7

The value and limitations of transgenic mouse models used in drug discovery for Alzheimer's disease: an update

Journal:

Expert Opinion on Drug Discovery

Year:

2012

Language:

english

File:

PDF, 533 KB

english, 2012

8

Mitochondrial genome sequencing: A valuable addition to whole exome sequencing for the molecular diagnosis of mitochondrial disorders

Balog, Amanda, Higgs, Jaimie, Retterer, Kyle, Arjona, Dolores, Warren-Mora, Nicole, Parsons, Kelly, Ye, Yizhou, Suchy, Sharon, Parikh, Sumit, Niyazov, Dmitriy, Tarnopolsky, Mark, Chung, Wendy, Bale, S

Journal:

Year:

2015

Language:

english

File:

PDF, 47 KB

english, 2015

9

Aβ immunization and anti-Aβ antibodies: potential therapies for the prevention and treatment of Alzheimer’s disease

David M Holtzman, Kelly R Bales, Steven M Paul, Ronald B DeMattos

Journal:

Advanced Drug Delivery Reviews

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002

10

MANCHESTER MEDICAL SOCIETY

Freeman, Gary, Brown, Thomas, Wallace, Karin, Bales, Kelly

Journal:

Year:

1932

Language:

english

File:

PDF, 177 KB

english, 1932

11

Apolipoprotein E Is Essential for Amyloid Deposition in the APPV717FTransgenic Mouse Model of Alzheimer's Disease

Kelly R. Bales, Tatyana Verina, David J. Cummins, Yansheng Du, Richard C. Dodel, Josep Saura, Cindy E. Fishman, Cynthia A. DeLong, Pedro Piccardo, Valerie Petegnief, Bernardino Ghetti and Steven M. Pa

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.94 MB

english, 1999

12

Rapid Detection of a Pentanucleotide Deletion Polymorphism in the Human Î±2-Macroglobulin Gene

Dodel, Richard C, Bales, Kelly R, Farlow, Martin R, Gasser, Thomas, Paul, Steven M, Du, Yansheng

Journal:

Clinical Chemistry

Year:

1999

File:

PDF, 176 KB

1999

13

Development of clickable active site-directed photoaffinity probes for γ-secretase

Christina J. Crump, Christopher W. am Ende, T. Eric Ballard, Nikolay Pozdnyakov, Martin Pettersson, De-Ming Chau, Kelly R. Bales, Yue-Ming Li, Douglas S. Johnson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 701 KB

english, 2012

14

Brain lipid metabolism, apolipoprotein E and the pathophysiology of Alzheimer's disease

Journal:

Neuropharmacology

Year:

2010

Language:

english

File:

PDF, 365 KB

english, 2010

15

The NF-κB/Rel family of proteins mediates Aβ-induced neurotoxicity and glial activation

Kelly R Bales, Yansheng Du, Richard C Dodel, Guang-Mei Yan, Elizabeth Hamilton-Byrd, Steven M Paul

Journal:

Molecular Brain Research

Year:

1998

Language:

english

File:

PDF, 507 KB

english, 1998

16

LONGITUDINAL, MULTI-MODALITY, MRI STUDIES OF GAMMA-SECRETASE INHIBITION IN AN APP-SW MOUSE MODEL OF ALZHEIMER'S DISEASE

Bedell, Barry J., Zehntner, Simone P., Rosahl, Thomas, Wood, Kathleen, Bales, Kelly R., Marconi, Michael A., Parker, Eric, Carbonell, Felix, Zijdenbos, Alex P.

Journal:

Alzheimer's & Dementia

Year:

2014

Language:

english

File:

PDF, 51 KB

english, 2014

17

O3-06-06 Normalization of impaired hippocampal acetylcholine efflux following anti-Aβ antibody administration

Kelly R. Bales, Eleni T. Tzavara, Su Wu, Steven M. Paul, Frank P. Bymaster, George G. Nomikos

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 159 KB

english, 2004

18

The role of alpha-1-antichymotrypsin (ACT) in abeta-amyloidosis of Alzheimer's disease, as studied in novel trigenic PDAPP, mapoe-knockout, GFAP-hACT transgenic mice strains

Lars Ng Nilsson, Giovanni DiCarlo, Marcia N. Gordon, David G. Morgan, Kelly R. Bales, Steven M. Paul, Eli Lilly, Huntington Potter

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 197 KB

english, 2000

19

Spontaneous amyloid-related imaging abnormalities of the microhemorrage and effusive/edematous types in aged APP+ presenilin 1 mice

James Goodman, Gary Freeman, William Angus, Thomas Brown, Peter Cheng-te Chou, Kelly Bales

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 164 KB

english, 2012

20

P3-444

Frasier, Mark, DeLong, Cynthia, Bales, Kelly, Merchant, Kalpana M.

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

21

A potential endophenotype for Alzheimer’s disease: Cerebrospinal fluid clusterin

Deming, Yuetiva, Xia, Jian, Lord, Jenny, Holmans, Peter, Bertelsen, Sarah, Cai, Yefei, Holtzman, David M., Morris, John C., Bales, Kelly R., Pickering, Eve H., Kauwe, John, Goate, Alison, Cruchaga, Ca

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 49 KB

english, 2015

22

Behavioral disturbances in transgenic mice overexpressing the V717F Β-amyloid precursor protein.

Dodart, Jean-Cosme, Meziane, Hamid, Mathis, Chantal, Bales, Kelly R., Paul, Steven M., Ungerer, Arielle

Journal:

Behavioral Neuroscience

Year:

1999

Language:

english

File:

PDF, 1.32 MB

english, 1999

23

Apolipoprotein E Markedly Facilitates Age-Dependent Cerebral Amyloid Angiopathy and Spontaneous Hemorrhage in Amyloid Precursor Protein Transgenic Mice

Fryer, John D., Taylor, Jennie W., DeMattos, Ronald B., Bales, Kelly R., Paul, Steven M., Parsadanian, Maia, Holtzman, David M.

Journal:

Journal of Neuroscience

Year:

2003

File:

PDF, 370 KB

2003

24

Sodium Salicylate and 17β-Estradiol Attenuate Nuclear Transcription Factor NF-κB Translocation in Cultured Rat Astroglial Cultures Following Exposure to Amyloid Aβ1-40 and Lipoplysaccharides

Richard Dodel, Yansheng Du, Kelly R. Bales, Feng Gao, Steven Paul

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 158 KB

english, 1999

25

Neurodegenerative disease research in the 21st century

Journal:

Drug Discovery Today

Year:

2004

Language:

english

File:

PDF, 334 KB

english, 2004

26

Effect of ponezumab on CSF biomarkers: Pooled analysis of phase IIa studies in subjects with mild-to-moderate Alzheimer's disease

Carol Cronenberger, Pam Schwartz, Kathryn Wright, Kelly Bales, Kaj Blennow, Henrik Zetterberg, Jaren Landen, Scot Styren, Nathan Chen, Brendon Binneman

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 95 KB

english, 2012

27

Gamma-secretase inhibitors and gamma-secretase modulators differentially regulate amyloid-beta 42 peptide generation in native brain membrane preparations from multiple species

Christine E.J. Oborski, Christine Parker, Martin Pettersson, Douglas S. Johnson, Rathna Iyer, Kelly Bales

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 45 KB

english, 2010

28

Phosphorylated Tau-Aβ42 Ratio as a Continuous Trait for Biomarker Discovery for Early-Stage Alzheimer’s Disease in Multiplex Immunoassay Panels of Cerebrospinal Fluid

Harari, Oscar, Cruchaga, Carlos, Kauwe, John S.K., Ainscough, Benjamin J., Bales, Kelly, Pickering, Eve H., Bertelsen, Sarah, Fagan, Anne M., Holtzman, David M., Morris, John C., Goate, Alison M.

Journal:

Biological Psychiatry

Year:

2014

Language:

english

File:

PDF, 1.66 MB

english, 2014

29

Development of preclinical models of vasogenic edema (VE) and microhemorrhage (MCH) using in-vivo bioimaging and histopathology

Freeman, Gary, Brown, Thomas, Goodman, James, Bales, Kelly

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 81 KB

english, 2011

30

Quantifying the defensive medicine contribution to primary care costs

Brateanu, Andrei, Schramm, Sarah, Hu, Bo, Boyer, Kristen, Nottingham, Kelly, Taksler, Glen B., Jolly, Stacey, Goodman, Kenneth, Misra-Hebert, Anita, Vakharia, Nirav, Hamilton, Aaron C., Bales, Robert,

Journal:

Journal of Medical Economics

Year:

2014

Language:

english

File:

PDF, 135 KB

english, 2014

31

Involvement of a Caspase-3-Like Cysteine Protease in 1-Methyl-4-Phenylpyridinium-Mediated Apoptosis of Cultured Cerebellar Granule Neurons

Yangshen Du, Richard C. Dodel, Kelly R. Bales, Ronald Jemmerson, Elizabeth Hamilton-Byrd, Steven M. Paul

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 1.05 MB

english, 1997

32

Use of multimetric statistical analysis to characterize and discriminate between the performance of four Alzheimer’s transgenic mouse lines differing in Aβ deposition

Ralph E Leighty, Lars N.G Nilsson, Huntington Potter, David A Costa, Mark A Low, Kelly R Bales, Steven M Paul, Gary W Arendash

Journal:

Behavioural Brain Research

Year:

2004

Language:

english

File:

PDF, 361 KB

english, 2004

33

Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms

David A. Costa, Jennifer R. Cracchiolo, Adam D. Bachstetter, Tiffany F. Hughes, Kelly R. Bales, Steven M. Paul, Ronald F. Mervis, Gary W. Arendash, Huntington Potter

Journal:

Neurobiology of Aging

Year:

2007

Language:

english

File:

PDF, 594 KB

english, 2007

34

Role of APOE in Alzheimer's disease-like neurodegeneration

David M. Holtzman, Anne M. Fagan, Kelly R. Bales, Ronald DeMattos, Michael C. Irizarry, Karen H. Ashe, Bradley T. Hyman, Steven M. Paul

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 396 KB

english, 2000

35

O4-04-02 Apolipoprotein E promotes the degradation of deposited amyloid-β peptides by adult mouse astrocytes

Milla Koistinaho, Suizhen Lin, Xin Wu, Michail Esterman, Jeffrey Hanson, Kelly R. Bales, Steven M. Paul

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 164 KB

english, 2004

36

P1-272: Association of a functional variant (I89V) in the high affinity choline transporter with Alzheimer’s disease

Yansheng Du, Xing Wei, Vincet Tagliabracci, Kelly R. Bales, Richard J. Higgs, Richard Dodel, Harald Hampel, Martin Farlow

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 53 KB

english, 2006

37

Transgene dependent, doxycycline-sensitive cognitive deficits in Tg4510 mutant mouse correlate with insoluble tau epitope accumulation

Robin L. Roof, Yoko Yabe, Tracy M. Brown, Sheryl A. McCarthy, Kelly R. Bales, Carol D. Hicks

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 43 KB

english, 2010

38

Pharmacokinetic/pharmacodynamic analysis of β-amyloid response following modulation of the gamma secretase enzyme

Wang, Ellen Q., Tseng, Elaine, Lu, Yasong, Becker, Stacey, Hudson, Emily, Zhang, Liming, Wood, Kathleen M., Bales, Kelly R., Marconi, Michael, Johnson, Doug S.

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 42 KB

english, 2010

39

Disruption of skin microbiota contributes to salamander disease

Bletz, Molly C., Kelly, Moira, Sabino-Pinto, Joana, Bales, Emma, Van Praet, Sarah, Bert, Wim, Boyen, Filip, Vences, Miguel, Steinfartz, Sebastian, Pasmans, Frank, Martel, An

Journal:

Proceedings Biological Sciences

Year:

2018

File:

PDF, 711 KB

2018

40

Use of YFP to study amyloid-β associated neurite alterations in live brain slices

Robert P. Brendza, Kelly Simmons, Kelly R. Bales, Steven M. Paul, Mark P. Goldberg, David M. Holtzman

Journal:

Neurobiology of Aging

Year:

2003

Language:

english

File:

PDF, 380 KB

english, 2003

41

P2-302 Apolipoprotein E is required for filamentous, but not diffuse, amyloid deposition in an APP/PS mouse model of Alzheimer's disease

Costa, David A., Bales, Kelly R., Paul, Steven M., Potter, Huntington

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 313 KB

english, 2004

42

Safety and Pharmacology of a Single Intravenous Dose of Ponezumab in Subjects With Mild-to-Moderate Alzheimer Disease

Landen, Jaren W., Zhao, Qinying, Cohen, Sharon, Borrie, Michael, Woodward, Michael, Billing, Clare B., Bales, Kelly, Alvey, Christine, McCush, Fred, Yang, Jerry, Kupiec, James W., Bednar, Martin M.

Journal:

Clinical Neuropharmacology

Year:

2013

Language:

english

File:

PDF, 1.09 MB

english, 2013

43

A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin

Deming, Yuetiva, Xia, Jian, Cai, Yefei, Lord, Jenny, Holmans, Peter, Bertelsen, Sarah, Holtzman, David, Morris, John C., Bales, Kelly, Pickering, Eve H., Kauwe, John, Goate, Alison, Cruchaga, Carlos

Journal:

Neurobiology of Aging

Year:

2016

Language:

english

File:

PDF, 658 KB

english, 2016

44

PDAPP; YFP double transgenic mice: A tool to study amyloid-β associated changes in axonal, dendritic, and synaptic structures

Robert P. Brendza, Cara O'Brien, Kelly Simmons, Daniel W. McKeel, Kelly R. Bales, Steven M. Paul, John W. Olney, Joshua R. Sanes, David M. Holtzman

Journal:

The Journal of Comparative Neurology

Year:

2003

Language:

english

File:

PDF, 848 KB

english, 2003

45

Minocycline blocks bilirubin neurotoxicity and prevents hyperbilirubinemia-induced cerebellar hypoplasia in the Gunn rat

Suizhen Lin, Xing Wei, Kelly R. Bales, Aaron B. C. Paul, Zhizhong Ma, Guangmei Yan, Steven M. Paul, Yansheng Du

Journal:

European Journal of Neuroscience

Year:

2005

Language:

english

File:

PDF, 496 KB

english, 2005

46

Emergence of a seizure phenotype in aged apolipoprotein epsilon 4 targeted replacement mice

Jesse M. Hunter, John R. Cirrito, Jessica L. Restivo, Robert D. Kinley, Patrick M. Sullivan, David M. Holtzman, Deanna Koger, Cynthia Delong, Suizhen Lin, Lingzhi Zhao, Feng Liu, Kelly Bales, Steven M

Journal:

Year:

2012

Language:

english

File:

PDF, 1011 KB

english, 2012

47

NF-κB mediates amyloid β peptide-stimulated activity of the human apolipoprotein E gene promoter in human astroglial cells

Yansheng Du, Xianming Chen, Xing Wei, Kelly R. Bales, David T. Berg, Steven M. Paul, Martin R. Farlow, Bryan Maloney, Yuan-Wen Ge, Debomoy K. Lahiri

Journal:

Molecular Brain Research

Year:

2005

Language:

english

File:

PDF, 441 KB

english, 2005

48

Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation

Lars N.G Nilsson, Gary W Arendash, Ralph E Leighty, David A Costa, Mark A Low, Marcos F Garcia, Jennifer R Cracciolo, Amyn Rojiani, Xin Wu, Kelly R Bales, Steven M Paul, Huntington Potter

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 576 KB

english, 2004

49

Diet-induced hyperlipidemia accelerates amyloid deposition in APPv717F transgenic mouse model of Alzheimer disease

Kelly R. Bales, Cindy Fishman, Cindy DeLong, Yansheng Du, William Jordan, Steven M. Paul

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 202 KB

english, 2000

50

Chronic ponezumab treatment reduces brain vascular amyloid in the PS1APP mouse model

O'Neill, Sharon, Pozdnyakov, Nikolay, YeQing Pi,, Caouette, David, Wood, Kathleen, Wentland, Jo-Ann, Bednar, Martin, Bales, Kelly, Samad, Tarek

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 52 KB

english, 2013

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